Reduce the Incidence and Severity of
Oral Mucositis

Oral mucositis is a debilitating and clinically significant side effect of many chemotherapy treatments. Clinical utility of the Chemo Mouthpiece is supported by a growing body of peer-reviewed evidence, including randomized controlled trials, subset analyses, case series, and health economic modeling.

• 46% decrease in oral pain¹
• 68% decrease in use and duration of opioid and non-opioid analgesics¹
• Efficacy across a wide range of cancer types and chemotherapy regimens¹
• Favorable patient-reported experience and tolerability¹
• Favorable outcomes observed in patients with ADC-associated oral mucositis²

Designed for use during chemotherapy treatment and at home following infusion, the Chemo Mouthpiece delivers consistent, uniform cooling across the oral cavity.

• 6 prefilled oral cooling devices and cooler
• Reusable throughout treatment—single patient, multi-use
• Designed for infusion and at-home use
• Patient-managed

1. Download the Referral Form

2. Submit the completed form to Zeal Specialty Pharmacy

3. Zeal supports: Benefits investigation, prior authorization, onboarding, Patient Assistance Program, and fulfillment

• Studied in patients across more than 17 cancer types and 30 chemotherapy regimens¹
• Designed for use before, during, and after infusion, with continued at-home use¹
• Portable, patient-managed oral cooling that supports treatment beyond the infusion center
• No device-related safety concerns reported in the clinical trial¹
• Supported by peer-reviewed evidence, including randomized clinical trials, health economic analyses, and published outcomes in ADC-associated oral mucositis^1-3

The Chemo Mouthpiece cools the entire oral cavity evenly. Darker areas represent colder temperatures.
(Data on file)

Patient Access & Financial Assistance

Zeal Specialty Pharmacy supports oncology practices with prescribing coordination, benefits investigation, prior authorization support, patient onboarding, and Patient Assistance Program (PAP) services.