Through Treatment, Together
Kayla's Story
When painful mouth sores (oral mucositis) from chemotherapy made Kayla fear she might not be able to continue treatment, finding the Chemo Mouthpiece® changed what came next.
Actual patient. Individual experiences vary.
Rx only. Please see Indication and Important Safety Information below and accompanying full Prescribing Information, also available at ChemoMouthpiece.com.
The Series
Through Treatment, Together is a documentary series about the impact mouth sores can have during chemotherapy — told by the people who have lived it and the clinicians who care for them.
Oral mucositis is a common side effect of many chemotherapy treatments that causes painful mouth sores. These sores can make it difficult to eat, drink, swallow, or speak and may disrupt cancer treatment.
The Chemo Mouthpiece is an FDA-cleared prescription oral cooling device designed to reduce the incidence and severity of chemotherapy induced oral mucositis in adult patients.
Behind every diagnosis is a personal experience. These films let patients share their experiences with oral mucositis during cancer treatment, in their own words.
Nobody should have to go through this alone.
Kayla · Episode One
Episodes
Kayla · in her own words
After her first chemotherapy infusion, painful mouth sores made it difficult for Kayla to eat—and even to smile at her children. She shares what changed when she began using the Chemo Mouthpiece and how it shaped the rest of her treatment experience.
Briele · patient and nurse
Briele experienced chemotherapy from a perspective few people do—as both a patient and a nurse. She shares her experience using the Chemo Mouthpiece during treatment.
David · founder and cancer survivor
After experiencing painful oral mucositis during chemotherapy, David knew there had to be a better way. He shares how a middle-of-the-night idea and his engineering background inspired the Chemo Mouthpiece.
The series continues with more patient and clinician stories. Read written experiences from other patients while you wait.
How it Works
The Chemo Mouthpiece cools the inside of the mouth to help reduce the incidence and severity of oral mucositis from chemotherapy.
Before
The device is kept at home in the freezer before and after use, so it is cold and ready for each treatment.
During
The mouthpiece cools the inside of the mouth throughout chemotherapy infusion.
After
Patients continue using the mouthpiece at home because chemotherapy continues circulating in the body even after they leave the infusion chair.
Clinical results
From a randomized, multi-site clinical trial of 164 adults receiving chemotherapy, published in Supportive Care in Cancer.
46%
Reduction in patients reporting oral pain vs control
P < .001
68%
Reduction in patients reporting opioid or analgesic use vs control
P = .007
Explore the clinical data and published study →
Zuniga et al. Supportive Care in Cancer. 2025.
If you are starting chemotherapy
The Chemo Mouthpiece is available by prescription. Your oncologist or infusion nurse can tell you whether it fits your treatment plan, and your care team can start the referral.
INDICATION FOR USE: (Rx only) The Chemo Mouthpiece® is intended to be used to cool the oral mucosa to reduce the incidence and severity of chemotherapy-induced oral mucositis in adult patients.
Do not use if the patient has a sensitivity to silicone. Stop using the device if skin irritation or sensitivities develop, or if the device leaks or does not maintain its material integrity. Do not bite; biting may cause the device to fail for its intended use or leak. Do not boil or put in the dishwasher to clean the device. Do not use the device without storing it in the freezer (before & after usage).
Do not use the device if you have severe respiratory distress or cardiac related problems. Caution should be taken when used with drugs that have an adverse event of cold aversion (e.g. oxaliplatin).
Do not use if the packaging or the Chemo Mouthpiece® is damaged.
Chemo Mouthpiece® devices are for use by a single patient. Devices are not to be shared with other patients.
Report all adverse events, complaints, or incidents to ChemoMouthpiece, LLC at 866-496-8858 or email support@chemomouthpiece.com.
FDA 510(k) Cleared.
Individual experiences vary. Please see the Indication and Important Safety Information on this page. Open on Vimeo instead